From Howstuffworks:
Fat cells are formed in the developing fetus during the third trimester of pregnancy, and later at the onset of puberty, when the sex hormones "kick in." It is during puberty that the differences in fat distribution between men and women begin to take form. One amazing fact is that fat cells generally do not generate after puberty -- as your body stores more fat, the number of fat cells remains the same. Each fat cell simply gets bigger! (There are two exceptions: the body might produce more fat cells if an adult gains a significant amount of weight or has liposuction performed.)
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